FVL (R506Q) Mutation Detection kit

Factor V Leiden-FVL Mutation Detection PCR Kit

Factor V Leiden (FVL) thrombophiliais a genetic disorder mostly found in 20-25% of patients suffering from venous thromboembolism (VTE). It is characterized by a poor anticoagulant response to activated protein C (APC) and an increased risk of venous thromboembolism. The term “factor V Leiden” refers to the specific G-to-A substitution at nucleotide 1691 in the gene for factor V that predicts a single amino acid replacement (R506Q) at one of three APC cleavage sites in the factor Va molecule. 

The diagnosis of factor V Leiden thrombophilia is suspected in individuals with a history of venous thromboembolism (VTE) [deep vein thrombosis (DVT) or pulmonary embolism], especially in women with a history of VTE during pregnancy or in association with oral contraceptive use, and families with a high incidence of VTE. 

MYLAB Factor V Leiden - FVL (R506Q) Mutation Detection PCR Kit

Mylab FVL Mutation Detection test is an in vitro diagnostic test for the detection and genotyping of the Factor V Leiden mutation – R506Q as an aid to diagnosis in the evaluation of patients with suspected thrombophilia by allele specific real time PCR.

FVL (R506Q) Mutation Detection Kit Features

FVL (R506Q) Mutation Detection Kit Contents

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